Cleavable Linkers are a class of conjugation linkers designed to connect two or more molecular entities, most commonly a monoclonal antibody and a cytotoxic drug payload. They are engineered to remain stable during circulation in the bloodstream while undergoing selective cleavage upon exposure to specific triggers, such as proteases, enzymes, light irradiation, or chemical stimuli. Cleavable linkers are widely used in pharmaceutical and biotechnology research and development, particularly in antibody-drug conjugates (ADCs), biolabeling, and chemical biology, where controlled release or separation of conjugated molecules is essential.