Azido-PEG12-Amido-Val-Cit-PAB-PNP serves as a clickable, cleavable linker that may be utilized in the formation of antibody-drug conjugates. The azido group participates in click chemistry with alkyne, BCN, DBCO via Click Chemistry. The Val-Cit linker was designed to be cleaved by cathepsin B. The PNP group is a good leaving group when reacting with amine-bearing payloads. Water solubility is enhanced via the PEG12 linker. Reagent grade, for research purpose.
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