TCO-PEG

TCO-PEG


TCO PEG linkers (reagents) are a class of PEG linkers with PEG attached to a TCO group (trans-cycloctene), TCO reagent is highly reactive with tetrazine in an inverse electron demand Diels Alder (IEDDA) reaction followed by a retro-Diels Alder reaction to eliminate nitrogen gas. This is a fast reaction with a second order rate constant of 2000 M 1 s 1 (in 9:1 methanol/water) allowing modification of biomolecules at very low concentrations. Reactions have also been performed using TCO or norbornenes as dienophiles at second order rates on the order of 1 M 1 s 1 in aqueous media. This reaction has been applied in labeling live cells, molecular imaging and other bioconjugation applications.

Catalog Product Name Structure M.W. Purity Pricing
TCO-PEG-NHS ester
BP-22417TCO-NHS esterMolecular structure of the compound: TCO-NHS ester267.395%Pricing
BP-41969TCO-PEG2-NHS esterMolecular structure of the compound: TCO-PEG2-NHS ester426.595%Pricing
BP-24147TCO-PEG3-NHS esterMolecular structure of the compound: TCO-PEG3-NHS ester470.595%Pricing
BP-22418TCO-PEG4-NHS esterMolecular structure of the compound: TCO-PEG4-NHS ester514.695%Pricing
BP-24156TCO-PEG6-NHS esterMolecular structure of the compound: TCO-PEG6-NHS ester602.795%Pricing
BP-24157TCO-PEG8-NHS esterMolecular structure of the compound: TCO-PEG8-NHS ester690.895%Pricing
BP-24123TCO-PEG12-NHS esterMolecular structure of the compound: TCO-PEG12-NHS ester86795%Pricing
BP-23970TCO-PEG24-NHS esterMolecular structure of the compound: TCO-PEG24-NHS ester1395.695%Pricing
BP-25127TCO-PEG36-NHS esterMolecular structure of the compound: TCO-PEG36-NHS ester1924.395%Pricing
TCO-PEG-TFP ester
BP-40298TCO-PEG4-TFP EsterMolecular structure of the compound: TCO-PEG4-TFP Ester565.6Pricing
BP-24129TCO-PEG8-TFP esterMolecular structure of the compound: TCO-PEG8-TFP ester741.895%Pricing
BP-24128TCO-PEG12-TFP esterMolecular structure of the compound: TCO-PEG12-TFP ester91895%Pricing
TCO-PEG-PNB
BP-22943TCO-PNB EsterMolecular structure of the compound: TCO-PNB Ester291.395%Pricing
TCO-PEG-Acid
BP-27908TCO-PEG2-acidMolecular structure of the compound: TCO-PEG2-acid329.498%Pricing
BP-24143TCO-PEG3-acidMolecular structure of the compound: TCO-PEG3-acid373.595%Pricing
BP-22420TCO-PEG4-acidMolecular structure of the compound: TCO-PEG4-acid417.595%Pricing
BP-24155TCO-PEG6-acidMolecular structure of the compound: TCO-PEG6-acid505.695%Pricing
BP-24133TCO-PEG8-acidMolecular structure of the compound: TCO-PEG8-acid593.795%Pricing
BP-25646TCO-PEG10-acidMolecular structure of the compound: TCO-PEG10-acid681.8Pricing
BP-24072TCO-PEG12-acidMolecular structure of the compound: TCO-PEG12-acid769.998%Pricing
BP-24087TCO-PEG24-acidMolecular structure of the compound: TCO-PEG24-acid1298.695%Pricing
BP-24068TCO-PEG36-acidMolecular structure of the compound: TCO-PEG36-acid1827.290%Pricing
TCO-PEG-Amine
BP-22422TCO-amine hydrochlorideMolecular structure of the compound: TCO-amine hydrochloride226.395%Pricing
BP-24158TCO-PEG2-amineMolecular structure of the compound: TCO-PEG2-amine300.495%Pricing
BP-24099TCO-PEG3-amineMolecular structure of the compound: TCO-PEG3-amine344.595%Pricing
BP-24101TCO-PEG4-amineMolecular structure of the compound: TCO-PEG4-amine388.595%Pricing
BP-24159TCO-PEG6-amineMolecular structure of the compound: TCO-PEG6-amine476.695%Pricing
BP-24162TCO-PEG8-amineMolecular structure of the compound: TCO-PEG8-amine564.798%Pricing
BP-25755TCO-PEG12-amineMolecular structure of the compound: TCO-PEG12-amine740.9Pricing
BP-25756TCO-PEG23-amineMolecular structure of the compound: TCO-PEG23-amine1225.5Pricing
BP-23320TCO-C3-PEG3-C3-amineMolecular structure of the compound: TCO-C3-PEG3-C3-amine372.595%Pricing
TCO-PEG-biotin
BP-23847TCO-PEG4-biotinMolecular structure of the compound: TCO-PEG4-biotin614.895%Pricing
BP-28222Biotin-PEG8-TCOMolecular structure of the compound: Biotin-PEG8-TCO79195%Pricing
BP-40631Biotin-PEG11-TCOMolecular structure of the compound: Biotin-PEG11-TCO923.295%Pricing
BP-28223Biotin-PEG12-TCOMolecular structure of the compound: Biotin-PEG12-TCO967.2Pricing
TCO-PEG-DBCO
BP-25757TCO-PEG2-DBCOMolecular structure of the compound: TCO-PEG2-DBCO587.7Pricing
BP-24160TCO-PEG4-DBCOMolecular structure of the compound: TCO-PEG4-DBCO675.895%Pricing
BP-25758TCO-PEG6-DBCOMolecular structure of the compound: TCO-PEG6-DBCO763.992%Pricing
BP-25744TCO-PEG8-DBCOMolecular structure of the compound: TCO-PEG8-DBCO852Pricing
BP-22423TCO-PEG12-DBCOMolecular structure of the compound: TCO-PEG12-DBCO1028.395%Pricing
BP-25759TCO-PEG24-DBCOMolecular structure of the compound: TCO-PEG24-DBCO1556.9Pricing
TCO-PEG-Maleimide
BP-29790TCO-PEG4-maleimideMolecular structure of the compound: TCO-PEG4-maleimide468.695%Pricing
BP-23872TCO-PEG9-maleimideMolecular structure of the compound: TCO-PEG9-maleimide759.995%Pricing
3,4-Dibromo-Mal-PEG-TCO
BP-416173,4-Dibromo-Mal-PEG12-TCOMolecular structure of the compound: 3,4-Dibromo-Mal-PEG12-TCO978.8Pricing
TCO-PEG-triethoxysilane
BP-24140TCO-PEG3-triethoxysilaneMolecular structure of the compound: TCO-PEG3-triethoxysilane576.895%Pricing
TCO-PEG-OH
BP-23975TCO-OHMolecular structure of the compound: TCO-OH126.290%Pricing
BP-24482TCO-PEG3-alcoholMolecular structure of the compound: TCO-PEG3-alcohol301.495%Pricing
TCO-PEG-TCO
BP-24444TCO-PEG2-TCOMolecular structure of the compound: TCO-PEG2-TCO452.695%Pricing
BP-25000TCO-PEG3-TCOMolecular structure of the compound: TCO-PEG3-TCO496.695%Pricing
BP-26123TCO-PEG6-TCOMolecular structure of the compound: TCO-PEG6-TCO628.898%Pricing
BP-24259TCO-PEG8-TCOMolecular structure of the compound: TCO-PEG8-TCO716.995%Pricing
BP-28867TCO-PEG12-TCOMolecular structure of the compound: TCO-PEG12-TCO893.195%Pricing
TCO-PEG-peptide
BP-24190Gly-Gly-Gly-PEG3-TCOMolecular structure of the compound: Gly-Gly-Gly-PEG3-TCO515.695%Pricing
BP-24462TCO-PEG4-Fmoc-Gly-Gly-GlyMolecular structure of the compound: TCO-PEG4-Fmoc-Gly-Gly-Gly781.995%Pricing
Biotin-PEG-TCO
BP-23847TCO-PEG4-biotinMolecular structure of the compound: TCO-PEG4-biotin614.895%Pricing
BP-28222Biotin-PEG8-TCOMolecular structure of the compound: Biotin-PEG8-TCO79195%Pricing
BP-40631Biotin-PEG11-TCOMolecular structure of the compound: Biotin-PEG11-TCO923.295%Pricing
BP-28223Biotin-PEG12-TCOMolecular structure of the compound: Biotin-PEG12-TCO967.2Pricing
Diazo-PEG-TCO
BP-26143Diazo-PEG3-TCOMolecular structure of the compound: Diazo-PEG3-TCO79498%Pricing
Bis-sulfone-PEG-TCO
BP-28211Bis-sulfone-PEG4-TCOMolecular structure of the compound: Bis-sulfone-PEG4-TCO871.1Pricing
m-PEG-TCO
BP-27872m-PEG4-TCOMolecular structure of the compound: m-PEG4-TCO359.598%Pricing
N-Methylaniline-PEG-TCO
BP-26290N-Methylaniline-PEG3-TCOMolecular structure of the compound: N-Methylaniline-PEG3-TCO519.798%Pricing
DOTA-PEG-TCO
BP-42060DOTA-PEG5-TCOMolecular structure of the compound: DOTA-PEG5-TCO81995%Pricing
Pacific Blue TCO
BP-41615TCO-PEG3-PBMolecular structure of the compound: TCO-PEG3-PB568.6Pricing