A nucleoside consists of a nucleobase linked to a five-carbon sugar-either ribose or 2'- deoxyribose. In nucleosides, the anomeric carbon of the sugar forms a glycosidic bond with the N9 position of a purine or the N1 position of a pyrimidine.
A nucleotide is a nucleoside with one or more phosphate groups attached. Nucleotides are the fundamental building blocks of nucleic acids, such as DNA and RNA, which are essential biomolecules in all forms of life. The four bases found in DNA are adenine (A), cytosine (C), guanine (G), and thymine (T), while in RNA, uracil (U) replaces thymine.
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