Ionizable Lipid

Ionizable Lipid


Ionizable lipids are protonated at low pH, which makes them positively charged, but they remain neutral at physiological pH. The pH-sensitivity of ionizable lipids is beneficial for mRNA delivery in vivo, because neutral lipids have less interactions with the anionic membranes of blood cells and, thus, improve the biocompatibility of lipid nanoparticles.

Ionizable Lipids promote endosome escape and reduce toxicity of lipid nanoparticle (LNP).

Catalog Product Name Structure M.W. Purity Pricing
ALC-0315 & Analogs
BP-25498ALC-0315Molecular structure of the compound: ALC-0315766.398%Pricing
BP-27892BP Lipid 226Molecular structure of the compound: BP Lipid 226738.297%Pricing
BP-27893BP Lipid 216Molecular structure of the compound: BP Lipid 216766.397%Pricing
BP-27894BP Lipid 217Molecular structure of the compound: BP Lipid 217794.498%Pricing
BP-27895BP Lipid 218Molecular structure of the compound: BP Lipid 218751.395%Pricing
BP-27896BP Lipid 219Molecular structure of the compound: BP Lipid 219780.398%Pricing
BP-27897BP Lipid 220Molecular structure of the compound: BP Lipid 220808.495%Pricing
BP-27898BP Lipid 221Molecular structure of the compound: BP Lipid 221794.498%Pricing
BP-27899BP Lipid 222Molecular structure of the compound: BP Lipid 222822.498%Pricing
BP-27900BP Lipid 223Molecular structure of the compound: BP Lipid 223780.398%Pricing
BP-27901BP Lipid 224Molecular structure of the compound: BP Lipid 224808.498%Pricing
BP-27902BP Lipid 225Molecular structure of the compound: BP Lipid 225836.498%Pricing
BP-29312BP Lipid 304Molecular structure of the compound: BP Lipid 304736.3Pricing
BP-29311BP Lipid 303Molecular structure of the compound: BP Lipid 303764.3Pricing
BP-28075BP Lipid 400Molecular structure of the compound: BP Lipid 400736.398%Pricing
BP-28082BP Lipid 700Molecular structure of the compound: BP Lipid 700714.185%Pricing
BP-28079Bis(N-2-ethoxyethyl 2-hexyldecanoate)amineMolecular structure of the compound: Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine670.1Pricing
BP-28083BP Lipid 800Molecular structure of the compound: BP Lipid 800858.390%Pricing
BP-28671BP Lipid 227Molecular structure of the compound: BP Lipid 227766.395%Pricing
BP-28186BP Lipid 1000Molecular structure of the compound: BP Lipid 1000794.498%Pricing
BP-40097BP Lipid 230Molecular structure of the compound: BP Lipid 230766.395%Pricing
BP-29923BP Lipid 229Molecular structure of the compound: BP Lipid 229822.498%Pricing
BP-40091BP Lipid 306Molecular structure of the compound: BP Lipid 306850.595%Pricing
SM-102 & Analogs
BP-25499SM-102Molecular structure of the compound: SM-102710.298%Pricing
BP-26359BP Lipid 101Molecular structure of the compound: BP Lipid 101626.098%Pricing
BP-26360BP Lipid 102Molecular structure of the compound: BP Lipid 102654.198%Pricing
BP-26361BP Lipid 103Molecular structure of the compound: BP Lipid 103682.198%Pricing
BP-26362BP Lipid 104Molecular structure of the compound: BP Lipid 104654.198%Pricing
BP-26363BP Lipid 105Molecular structure of the compound: BP Lipid 105682.1Pricing
BP-26364BP Lipid 106Molecular structure of the compound: BP Lipid 106710.297%Pricing
BP-26365BP Lipid 107Molecular structure of the compound: BP Lipid 107682.198%Pricing
BP-26127Lipid 5Molecular structure of the compound: Lipid 5710.295%Pricing
BP-26367BP Lipid 109Molecular structure of the compound: BP Lipid 109738.298%Pricing
BP-26368BP Lipid 110Molecular structure of the compound: BP Lipid 110640.1Pricing
BP-26369BP Lipid 111Molecular structure of the compound: BP Lipid 111668.1Pricing
BP-26370BP Lipid 112Molecular structure of the compound: BP Lipid 112696.297%Pricing
BP-26371BP Lipid 113Molecular structure of the compound: BP Lipid 113654.198%Pricing
BP-26372BP Lipid 114Molecular structure of the compound: BP Lipid 114682.198%Pricing
BP-26373BP Lipid 116Molecular structure of the compound: BP Lipid 116640.190%Pricing
BP-26374BP Lipid 117Molecular structure of the compound: BP Lipid 117668.1Pricing
BP-26375BP Lipid 118Molecular structure of the compound: BP Lipid 118696.298%Pricing
BP-26376BP Lipid 119Molecular structure of the compound: BP Lipid 119668.1Pricing
BP-26377BP Lipid 120Molecular structure of the compound: BP Lipid 120696.2Pricing
BP-26378BP Lipid 121Molecular structure of the compound: BP Lipid 121724.2Pricing
BP-26379BP Lipid 122Molecular structure of the compound: BP Lipid 122654.195%Pricing
BP-26380BP Lipid 123Molecular structure of the compound: BP Lipid 123682.196%Pricing
BP-26381BP Lipid 124Molecular structure of the compound: BP Lipid 124710.298%Pricing
BP-26382BP Lipid 125Molecular structure of the compound: BP Lipid 125668.1Pricing
BP-26383BP Lipid 126Molecular structure of the compound: BP Lipid 126696.290%Pricing
BP-26384BP Lipid 127Molecular structure of the compound: BP Lipid 127724.2Pricing
BP-26467BP Lipid 210Molecular structure of the compound: BP Lipid 210738.2Pricing
BP-26466BP Lipid 209Molecular structure of the compound: BP Lipid 209738.298%Pricing
BP-26468BP Lipid 211Molecular structure of the compound: BP Lipid 211766.3Pricing
BP-26470BP Lipid 213Molecular structure of the compound: BP Lipid 213766.3Pricing
BP-26469BP Lipid 212Molecular structure of the compound: BP Lipid 212766.3Pricing
BP-26471BP Lipid 214Molecular structure of the compound: BP Lipid 214794.495%Pricing
BP-26385BP Lipid 128Molecular structure of the compound: BP Lipid 128640.196%Pricing
BP-26386BP Lipid 129Molecular structure of the compound: BP Lipid 129668.198%Pricing
BP-26387BP Lipid 130Molecular structure of the compound: BP Lipid 130696.2Pricing
BP-26388BP Lipid 131Molecular structure of the compound: BP Lipid 131668.197%Pricing
BP-26389BP Lipid 132Molecular structure of the compound: BP Lipid 132696.2Pricing
BP-26390BP Lipid 133Molecular structure of the compound: BP Lipid 133724.2Pricing
BP-26391BP Lipid 134Molecular structure of the compound: BP Lipid 134696.2Pricing
BP-26392BP Lipid 135Molecular structure of the compound: BP Lipid 135724.290%Pricing
BP-26393BP Lipid 136Molecular structure of the compound: BP Lipid 136752.396%Pricing
BP-26394BP Lipid 137Molecular structure of the compound: BP Lipid 137654.1Pricing
BP-26395BP Lipid 138Molecular structure of the compound: BP Lipid 138682.198%Pricing
BP-26396BP Lipid 139Molecular structure of the compound: BP Lipid 139710.2Pricing
BP-26397BP Lipid 140Molecular structure of the compound: BP Lipid 140668.198%Pricing
BP-26398BP Lipid 141Molecular structure of the compound: BP Lipid 141696.2Pricing
BP-26399BP Lipid 142Molecular structure of the compound: BP Lipid 142724.298%Pricing
BP-26400BP Lipid 143Molecular structure of the compound: BP Lipid 143654.1Pricing
BP-26401BP Lipid 144Molecular structure of the compound: BP Lipid 144682.1Pricing
BP-26402BP Lipid 145Molecular structure of the compound: BP Lipid 145710.2Pricing
BP-26403BP Lipid 146Molecular structure of the compound: BP Lipid 146682.1Pricing
BP-26404BP Lipid 147Molecular structure of the compound: BP Lipid 147710.2Pricing
BP-26405BP Lipid 148Molecular structure of the compound: BP Lipid 148738.2Pricing
BP-26406BP Lipid 149Molecular structure of the compound: BP Lipid 149668.1Pricing
BP-26407BP Lipid 150Molecular structure of the compound: BP Lipid 150696.2Pricing
BP-26408BP Lipid 151Molecular structure of the compound: BP Lipid 151724.2Pricing
BP-26409BP Lipid 152Molecular structure of the compound: BP Lipid 152682.1Pricing
BP-26410BP Lipid 153Molecular structure of the compound: BP Lipid 153710.2Pricing
BP-26411BP Lipid 154Molecular structure of the compound: BP Lipid 154738.2Pricing
BP-40239BP Lipid 313Molecular structure of the compound: BP Lipid 313740.295%Pricing
BP-29309BP Lipid 301Molecular structure of the compound: BP Lipid 301754.2Pricing
BP-29310BP Lipid 302Molecular structure of the compound: BP Lipid 302768.3Pricing
BP-40280BP Lipid 802Molecular structure of the compound: BP Lipid 802800.395%Pricing
BP-40226BP Lipid 801Molecular structure of the compound: BP Lipid 801842.395%Pricing
D-Lin-DMA & Analogs
BP-29593DLin-DMAMolecular structure of the compound: DLin-DMA616.1Pricing
BP-40125D-Lin-MC2-DMAMolecular structure of the compound: D-Lin-MC2-DMA628.1Pricing
BP-25497D-Lin-MC3-DMAMolecular structure of the compound: D-Lin-MC3-DMA642.196%Pricing
BP-40126D-Lin-MC4-DMAMolecular structure of the compound: D-Lin-MC4-DMA656.1Pricing
BP-25708DLin-KC2-DMAMolecular structure of the compound: DLin-KC2-DMA642.195%Pricing
BP-404502,2-Di(9Z,12Z)-9,12-octadecadien-1-yl-1,3-dioxolane-4-ethanolMolecular structure of the compound: 2,2-Di(9Z,12Z)-9,12-octadecadien-1-yl-1,3-dioxolane-4-ethanol615.095%Pricing
BP-29594YSK05Molecular structure of the compound: YSK05628.1Pricing
BP-29577AA3-DLinMolecular structure of the compound: AA3-DLin699.1Pricing
BP-28672Lipid A9Molecular structure of the compound: Lipid A9905.598%Pricing
BP-28064L319Molecular structure of the compound: L319678.195%Pricing
BP-40710Lipid A6Molecular structure of the compound: Lipid A6702.1Pricing
BP-25707DODMAMolecular structure of the compound: DODMA620.197%Pricing
BP-29709ATX-001Molecular structure of the compound: ATX-001695.1Pricing
BP-29583ATX-100Molecular structure of the compound: ATX-100755.3Pricing
BP-40113Lipid 2Molecular structure of the compound: Lipid 2655.095%Pricing
BP-2958680-O16BMolecular structure of the compound: 80-O16B767.3Pricing
BP-40124BP Lipid 309Molecular structure of the compound: BP Lipid 309807.495%Pricing
BP-40117BP Lipid 307Molecular structure of the compound: BP Lipid 307863.595%Pricing
BP-2954893-O17SMolecular structure of the compound: 93-O17S782.395%Pricing
BP-2959693-O17OMolecular structure of the compound: 93-O17O750.2Pricing
BP-29591NT1-O14BMolecular structure of the compound: NT1-O14B769.3Pricing
BP-29592TCL053Molecular structure of the compound: TCL053874.4Pricing
BP-40634BP Lipid 318Molecular structure of the compound: BP Lipid 3181042.795%Pricing
BP-40445BP Lipid 316Molecular structure of the compound: BP Lipid 316774.295%Pricing
BP-40633BP Lipid 317Molecular structure of the compound: BP Lipid 317778.295%Pricing
BP-40705BP Lipid 320Molecular structure of the compound: BP Lipid 3201068.795%Pricing
BP-29589Lipid C24Molecular structure of the compound: Lipid C24876.5Pricing
BP-406322-[Di-(9Z,12Z)-9,12-octadecadien-1-ylamino]ethyl 4-methyl-1-piperazinepropanoateMolecular structure of the compound: 2-[Di-(9Z,12Z)-9,12-octadecadien-1-ylamino]ethyl 4-methyl-1-piperazinepropanoate712.295%Pricing
BP-40412BP Lipid 315Molecular structure of the compound: BP Lipid 315851.495%Pricing
BP-40658BP Lipid 319Molecular structure of the compound: BP Lipid 319749.395%Pricing
LP01 & Analogs
BP-26809LP01Molecular structure of the compound: LP01852.398%Pricing
BP-40215BP Lipid 312Molecular structure of the compound: BP Lipid 312826.395%Pricing
BP-40214BP Lipid 311Molecular structure of the compound: BP Lipid 311782.295%Pricing
BP-29316BP Lipid 308Molecular structure of the compound: BP Lipid 308808.295%Pricing
BP-40354BP Lipid 314Molecular structure of the compound: BP Lipid 314823.395%Pricing
CL1 & Analogs
BP-29547CL1Molecular structure of the compound: CL1588.098%Pricing
BP-40136BP Lipid 310Molecular structure of the compound: BP Lipid 310618.095%Pricing
BP-40439BP Lipid 323Molecular structure of the compound: BP Lipid 323600.095%Pricing
BP-40415BP Lipid 321Molecular structure of the compound: BP Lipid 321616.095%Pricing
BP-40416BP Lipid 322Molecular structure of the compound: BP Lipid 322673.195%Pricing
Multi chargeable lipid
BP-28065306Oi10Molecular structure of the compound: 306Oi10994.698%Pricing
BP-29588306-O12B-3Molecular structure of the compound: 306-O12B-3974.6Pricing
BP-29587306-O12BMolecular structure of the compound: 306-O12B1251.1Pricing
BP-29582113-O12BMolecular structure of the compound: 113-O12B1223.0Pricing
BP-29579113-O16BMolecular structure of the compound: 113-O16B1447.5Pricing
BP-40400306Oi9-cis2Molecular structure of the compound: 306Oi9-cis2930.495%Pricing
BP-40712304O13Molecular structure of the compound: 304O13951.6Pricing
BP-29067BAMEA-O16BMolecular structure of the compound: BAMEA-O16B1114.995%Pricing
BP-40351Al-28Molecular structure of the compound: Al-281143.0Pricing
BP-40622C3-K2-E14Molecular structure of the compound: C3-K2-E141136.9Pricing
BP-2906698N12-5Molecular structure of the compound: 98N12-51343.398%Pricing
BP-40711G0-C14Molecular structure of the compound: G0-C141791.0Pricing
BP-29590cKK-E12Molecular structure of the compound: cKK-E12993.6Pricing
BP-29581OF-02Molecular structure of the compound: OF-021314.2Pricing
BP-40713OF-C4-Deg-LinMolecular structure of the compound: OF-C4-Deg-Lin1594.5Pricing
BP-26474C12-200Molecular structure of the compound: C12-2001137.095%Pricing
BP-40709TT3Molecular structure of the compound: TT31388.4Pricing
BP-20309C13-112-tri-tailMolecular structure of the compound: C13-112-tri-tail743.395%Pricing
BP-20311C13-113-tri-tailMolecular structure of the compound: C13-113-tri-tail712.395%Pricing
BP-20308C13-112-tetra-tailMolecular structure of the compound: C13-112-tetra-tail941.695%Pricing
BP-20310C13-113-tetra-tailMolecular structure of the compound: C13-113-tetra-tail910.695%Pricing
Other ionizable lipid
BP-29580SSPalmMMolecular structure of the compound: SSPalmM717.2Pricing
BP-29578SSPalmO-PheMolecular structure of the compound: SSPalmO-Phe1173.8Pricing
BP-29595Lipid 29Molecular structure of the compound: Lipid 29860.4Pricing
BP-295859A1P9Molecular structure of the compound: 9A1P9491.7Pricing