BP Lipid 560 is a novel hybrid of TCL053 and IAJD93 ionizable lipids. The key feature is the introduction of monounsaturated ether lipids derived from oleic acid. The ionizable head group consists of a 2-hydroxyethyl piperazine spacer three carbon atoms long via a biodegradable ester linkage. This compound may be used in lipid nanoparticle (LNP) formulations for drug or mRNA delivery applications.
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