BP Lipid 563 is a novel hybrid of TCL053 and IAJD93 ionizable lipids. The key feature is the introduction of unsaturated ether lipids derived from linoleic acid. The ionizable head group consists of a multichargeable 3-(3-hydroxyazetidine)propanoate biodegradable ester. This compound may be used in lipid nanoparticle (LNP) formulations for drug or mRNA delivery applications.
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