DODAP (18:1)

DODAP (18:1)

DODAP (18:1) is an ionizable lipid with lower cytotoxicity and high transfection efficiency. DODAP is neutral at physiological pH, but acquires a positive charge inside the endosome due to the protonation of free amines when pH is lower than its pKa (<7).

Molecular structure of the compound BP-28060
    • Unit
    • Price
    • Qty
    • 100 MG
    • $150.00
    • 250 MG
    • $230.00
    • 500 MG
    • $350.00
    • 1 G
    • $600.00

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Product Citations

  1. https://www.nature.com/articles/s41541-025-01349-w
    Lipid
  2. Ko, K. H., Lee, S. H., Choi, Y. H., Kang, S. M., Yang, H. S., Lee, S. M., ... & Cha, S. B. (2025). Lipid nanoparticle encapsulated TLR3 agonist adjuvant elicits potent T cell immunity against cancer and viruses. npj Vaccines.
    https://www.nature.com/articles/s41541-025-01349-w