BP Lipid 546 is a novel, multifunctional, IAJD93 analog featuring three cyclopropyl ether lipid tails and a 2-hydroxyethyl piperazine head group linked via a biodegradable ester bond. The introduction of the cyclopropane moieties, structural motifs naturally present in bacterial membranes, is intended to assist in the next generation of lipid nanoparticle research for drug or mRNA delivery applications.
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