TCO-PEG3-NHS ester

TCO-PEG3-NHS ester

TCO-PEG3-NHS Ester is a PEG linker containing a TCO moiety and a NHS ester. The hydrophilic PEG spacer increases water-solubility and a decreases steric hindrance during ligation. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Please contact us for GMP-grade inquiries. The half-life of TCO is short as it will naturally isomerize into CCO (cis-cycloctene) and lose the reactivity. TCO compound is not recommended for long term storage.

Molecular structure of the compound BP-24147
    • Unit
    • Price
    • Qty
    • 25 MG
    • $180.00
    • 100 MG
    • $490.00
    • 250 MG
    • $980.00

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Product Citations

  1. Tran, T. D., Meadows-Graves, S. J., Haio, A. R., Varga, A. I., & Luallen, R. J. (2025). A type III secretion system is required for Bordetella atropi host cell invasion in vivo. bioRxiv, 2025-06.
    https://www.biorxiv.org/content/10.1101/2025.06.23.660806v1.full