TCO-PEG6-NHS ester

TCO-PEG6-NHS ester

TCO-PEG6-NHS Ester is a PEG crosslinker containing a TCO moiety and a NHS ester. The hydrophilic PEG spacer increases water-solubility and decreases steric hindrance during ligation. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Please contact us for GMP-grade inquiries. The half-life of TCO is short as it will naturally isomerize into CCO (cis-cycloctene) and lose the reactivity. TCO compound is not recommended for long term storage.

Molecular structure of the compound BP-24156
    • Unit
    • Price
    • Qty
    • 25 MG
    • $220.00
    • 50 MG
    • $375.00
    • 100 MG
    • $680.00

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Product Citations

  1. Browne, A. S., Fang, J., Elsharkawy, A., Jia, T., Reboli, E., Luo, Y., ... & Iyer, S. S. (2025). Multilayer Fluorescent Immunoassay for Early and Sensitive Dengue Virus Detection Using Host and Viral Biomarkers. Bioconjugate Chemistry.
    https://pubs.acs.org/doi/full/10.1021/acs.bioconjchem.5c00153