DBCO-PEG8-Val-Cit-PAB-MMAE

DBCO-PEG8-Val-Cit-PAB-MMAE


DBCO-PEG8-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The DBCO group is a click chemistry handle which readily reacts with azide groups while the Val-Cit dipeptide is a protease-cleavable motif which releases the MMAE warhead into cells via an elimination mechanism within the PAB fragment.

Molecular structure of the compound BP-40446
    • Unit
    • Price
    • Qty
    • 10 MG
    • $680.00
    • 25 MG
    • $1350.00
    • 50 MG
    • $1950.00
    • 100 MG
    • $2900.00

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