Azido-PEG2-Val-Cit-PAB-Exatecan is a Cathepsin-cleavable peptide linker attached to an exatecan payload for the employment of antibody drug conjugates (ADCs). The azido group reacts with alkynes or strained cycloocytnes such as BCN, DBCO through click chemistry. The PEG spacer increases aqueous solubility of the compound.
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