NHS ester-PEG8-Val-Cit-PAB-MMAF

NHS ester-PEG8-Val-Cit-PAB-MMAF


NHS ester-PEG8-Val-Cit-PAB-MMAF is designed for use in antibody-drug conjugates (ADCs). It features MMAF, a potent antitubulin agent that disrupts cell division by preventing tubulin polymerisation. The Val-Cit sequence is specifically cleaved by the enzyme Cathepsin B. The NHS ester group at the end allows for efficient and direct bonding with amine groups found in various molecules. Additionally, the included PEG8 segment significantly boosts the conjugate's solubility in water.

Molecular structure of the compound BP-43527
    • Unit
    • Price
    • Qty
    • 10 MG
    • $870.00
    • 25 MG
    • $1500.00
    • 50 MG
    • $2600.00

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