Picolyl azide-PEG4-Val-Cit-PAB-MMAE functions as a linker-payload conjugate consisting of a protease-sensitive Val-Cit dipeptide for cleavage, cytotoxic MMAE payload for tumor cell destruction, and picolyl azide that assists with a copper-chelating system within its structure, lowering the amount of copper catalyst required in the CuAAC reaction for the azide. The PEG4 units impart solubility in aqueous media. Reagent grade, for research purpose.
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