DBCO-PEG8-Val-Cit-PAB-Exatecan serves as a linker-payload containing a cathepsin-cleavable Val-Cit dipeptide with an exatecan payload, and it may be applied in the synthesis of antibody-drug conjugates (ADCs). The DBCO serves as a click chemistry handle for reacting with azides without copper. The PEG8 spacer increases the water solubility of the molecule. Reagent grade, for research purpose.
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