NHS ester-Val-Cit-PAB-MMAE

NHS ester-Val-Cit-PAB-MMAE


NHS ester-Val-Cit-PAB-MMAE serves as a precursor of antibody-drug conjugates (ADCs). It contains a cathepsin-cleavable Val-Cit dipeptide and MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody which directs it toward cancer cells. The NHS ester is able to react specifically and efficiently with amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-41657
    • Unit
    • Price
    • Qty
    • 1 MG
    • $540.00
    • 5 MG
    • $1500.00
    • 10 MG
    • $2400.00

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