endo-BCN-PEG8-Val-Cit-PAB-MMAE

endo-BCN-PEG8-Val-Cit-PAB-MMAE


endo-BCN-PEG8-Val-Cit-PAB-MMAE is an ADC linker featuring a BCN group, a hydrophilic PEG spacer, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The BCN group is a click chemistry handle which readily reacts with azide groups on a target molecule to form stable triazole linkages, while the Val-Cit dipeptide is a protease-cleavable motif which releases the MMAE warhead into cells via an elimination mechanism within the PAB structure.

Molecular structure of the compound BP-40734
    • Unit
    • Price
    • Qty
    • 5 MG
    • $890.00
    • 10 MG
    • $1500.00
    • 25 MG
    • $2850.00

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