MC-Gly-Gly-Phe-Gly (MC-GGFG) is a protease-cleavable tetrapeptide linker featuring the GGFG (Gly-Gly-Phe-Gly) sequence and a maleimide (MC) group. It can be used in the synthesis of antibody-drug conjugates (ADCs) by attaching to payloads and antibodies. The maleimide group can react with a thiol group to form a covalent bond.
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