Depatuxizumab Mafodotin (Depatux-M, ABT-414) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F (MMAF) via a stable maleimidocaproyl link. Depatuxizumab Mafodotin is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM). This product is for research use only.
Product Details |
Species Reactivity | Human |
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Type | Antibody-drug conjugate |
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ADC antibody | Depatuxizumab (anti-EGFR) |
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ADC cytotoxin (drug) | MMAF |
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Immunogen | Human EGFR |
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DAR (Drug to Antibody Ratio) | 3~4 |
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Purity | 98% |
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Molecular Weight | N/A |
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Storage Condition | Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
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Storage Buffer | 1xPBS |