Trastuzumab duocarmazine ((vic)-Trastuzumab duocarmazine) is a HER2-targeting ADC that is recognized and cleaved by histone B in tumor cells and selectively targets tumor cells. Trastuzumab duocarmazine has anti-tumor activity and can be used in cancer research related to uterine and ovarian sarcomas. Trastuzumab duocarmazine has a Drug-to-antibody ratio (DAR) of 4.0, it's molecular weight is 145kDa. This product is for research use only.
Product Details |
Species Reactivity | Human |
---|
Type | Antibody-drug conjugate |
---|
ADC antibody | Trastuzumab (anti-HER2) |
---|
ADC cytotoxin (drug) | MMAE |
---|
Immunogen | Human HER2 |
---|
DAR (Drug to Antibody Ratio) | 2.8 |
---|
Purity | 99% |
---|
Molecular Weight | 145KDa |
---|
Storage Condition | Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
---|
Storage Buffer | 1xPBS |