Glembatumumab vedotin

Glembatumumab vedotin (CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma. This product is for research use only.

Product Details
Species Reactivity	Human
Type	Antibody-drug conjugate
ADC antibody	Glembatumumab (anti-GPNMB)
ADC cytotoxin (drug)	MMAE
Immunogen	Human GPNMB
DAR (Drug to Antibody Ratio)	N/A
Purity	99%
Molecular Weight	63.92KDa
Storage Condition	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Storage Buffer	1xPBS