Tusamitamab Ravtansine (SAR-408701), is an antibody-drug conjugate (ADC) composed of CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) targeting antibody and a cytotoxic maytansinoid tubulin inhibitor DM4, via a cleavable linker. Tusamitamab ravtansine has an average drug-to-antibody ratio (DAR) of n = 3.8. It has an approximate molecular weight of 148 kDa.This product is for research use only.
Product Details |
Species Reactivity | Human |
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Type | Antibody-drug conjugate |
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ADC antibody | Tusamitamab (Anti-CEACAM5) |
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ADC cytotoxin (drug) | DM4 |
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Immunogen | Human CEACAM5 |
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DAR (Drug to Antibody Ratio) | ~3.8 |
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Purity | 99% |
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Molecular Weight | 148kDa |
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Storage Condition | Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
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Storage Buffer | 1x PBS |