Cetuximab (anti-EGFR: epidermal growth factor receptor), marketed under the brand name Erbitux, is an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation. The antibody-drug conjugate (ADC) Cetuximab saratolacan, also known as Akalux, is a novel treatment for unresectable locally advanced or recurrent head and neck cancer has been approved in Japan. This ADC drug is a conjugate of Cetuximab with a photosensitizer called IR700 through linker. This biosimilar antibody is used for research only. MW: 145.781 KD.
Product Details |
Species Reactivity | Human |
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Host/Isotype | Human IgG1 |
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Class | Monoclonal |
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Type | Recombinant Antibody |
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Immunogen | Human EGFR, 0.39 nM(Kd) |
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Clone | Cetuximab biosimilar |
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Conjugate | Unconjugated |
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Purity | 99% |
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Molecular Weight | 145.781 KD |
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Protein Concentration | 1mg/ml |
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Storage Condition | Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
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Storage Buffer | 100mM Pro-Ac, 20mM Arg-Ac, pH 5.0 |