Sacituzumab (anti-Trop-2) is a fully humanized IgG1 kappa monoclonal antibody that targeting binds Trop-2 protein found on the surface of cancer cells. It can be used in the synthesis of an antibody-drug conjugate (ADC) through conjugate Sacituzumab with topoisomerase inhibitor drug (SN38). The ADC Sacituzumab govitecan, sold under the brand name Trodelvy, used primarily for the treatment of certain types of cancer, including metastatic triple-negative breast cancer and metastatic urothelial cancer. This biosimilar antibody is used for research only.
Product Details |
Species Reactivity | Human |
---|
Host/Isotype | Human IgG1 |
---|
Class | Monoclonal |
---|
Type | Recombinant Antibody |
---|
Immunogen | Human Trop2 |
---|
Clone | Sacituzumab biosimilar |
---|
Conjugate | Unconjugated |
---|
Purity | 99% |
---|
Protein Concentration | 1mg/ml |
---|
Storage Condition | Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
---|
Storage Buffer | 100mM Pro-Ac, 20mM Arg-Ac, pH 5.0 |