TMX-4113 is a FPFT-2216 analog and degrader of PDE6D and CK1α. TMX-4113 does not inhibit the growth of KRASG12C-dependent cancer cells. TMX-4113 can be used in the research of multiple myeloma, pancreatic ductal adenocarcinoma, non-small cell lung cancer and gastric adenocarcinoma.
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