As a fundamental component of plasma membranes, cholesterol serves its essential biological roles by controlling cell membrane structural and functional integrity. It also acts as a signaling molecule to interact with various membrane proteins to modulate their physiological functions. Cholesterol is also a biosynthetic precursor of many other biologically critical molecules such as steroid hormones, bile acids and Vitamin D. It is critical to understand and monitor cholesterol's role in membrane's physiological behavior and its interaction with proteins involved in signaling and transport pathways. Hence, a cholesterol derivative that can faithfully mimic its physicochemical properties enables scientists to investigate cholesterol's roles by visualizing and monitoring its precise localization and dynamic distribution. The BODIPY labeled cholesterol probe has a tunable fluorescence emission range from 500-700 nm and high photostability with less sensitivity to change in solvent polarity and pH. BODIPY labeled cholesterol has similar properties to that of the native cholesterol. This serves as a cholesterol marker for live cells and aids in trafficking intracellular cholesterol. It might also help in indicating lipid storage diseases.
Usually ships within 24 hours.