Entrectinib
Entrectinib (NMS-E628) is an orally active, brain-penetrant inhibitor of TrkA/B/C, ROS1, and ALK (IC50s = 1, 3, 5, 12, and 7 nM, respectively). It induces apoptosis, cell cycle arrest, and has antitumor activity while also reducing bleomycin-induced lung fibrosis in mice. Reagent grade, for research use only.

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Catalog:
BP-43651
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Name:
Entrectinib
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Formula:
C31H34F2N6O2
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MW:
560.7
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CAS:
1108743-60-7
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Purity:
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Ships Within:
24 Hours
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Storage Condition:
-20°C
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Shipping:
Ambient Temperature
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NMR:
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SDS:
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