Sotorasib

Sotorasib

Sotorasib (AMG-510) is a first-in-class, orally bioavailable KRAS G12C covalent inhibitor that locks KRAS G12C in an inactive GDP-bound state. It reduces tumor volume in KRAS G12C models and inhibits ERK1/2 phosphorylation (IC50 = 68 nM in MIA PaCa-2 cells). Reagent grade, for research use only.

Molecular structure of the compound BP-43642
    • Unit
    • Price
    • Qty
    • 100 MG
    • $150.00
    • 250 MG
    • $280.00
    • 500 MG
    • $430.00
    • 1 G
    • $640.00

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