NHS-PEG5-bis-PEG3-methyltetrazine is a branched PEG linker designed for high-performance bioconjugation. Its structure incorporates an NHS ester for rapid amine coupling and two methyltetrazine groups that efficiently undergo click reactions with TCO-modified entities. The PEG spacers impart hydrophilicity. The branched architecture provides multiple attachment sites, thereby optimizing payload conjugation for ADC formats.
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