27-Hydroxycholesterol is an endogenous oxysterol with diverse biological functions, acting as a selective estrogen receptor modulator (SERM) and a liver X receptor (LXR) agonist. It is a cholesterol metabolite produced by CYP27A1. 27-HC suppresses lipid accumulation by downregulating lipogenic and adipogenic genes in 3T3-L1 cells and promotes cell proliferation while increasing resistance to docetaxel-induced apoptosis in prostate epithelial cells. Reagent grade, for research purpose.
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