Azide-PEG4-Gly-Gly-L-Phe-N-[(carboxymethoxy)methyl]Glycinamide-MMAE represents a unique linker-payload conjugate which may be utilized in the synthesis of antibody-drug conjugates. The terminal azide participates in copper-catalyzed click reactions with BCN, DBCO, and alkynes. The MMAE serves as a drug payload for destroying tumor cells. The PEG linkage between the azide and peptide linker bolsters the aqueous solubility of the compound.
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