MMAE

MMAE

MMAE is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclonal antibody (MAB) which directs it to the cancer cells. Monomethyl auristatin E or MMAE is 100-1000 times more potent than doxorubicin. It is a very potent antimitotic agent that inhibits cell division by blocking the polymerization of tubulin. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22278
    • Unit
    • Price
    • Qty
    • 100 MG
    • $280.00
    • 250 MG
    • $490.00
    • 500 MG
    • $680.00
    • 1 G
    • $995.00

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Product Citations

  1. Samantha RB, Courtney PJ, Siteng F, et al. Thiolation of Q295: Site-Specific Conjugation of Hydrophobic Payloads without the Need for Genetic Engineering. Molecular Pharmaceuticals. 2019; 16(6): pp. 2795-2805.
    https://pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.9b00323