LC-MB12 is an orally active PROTAC designed for the degradation of FGFR2. This compound integrates a FGFR2 inhibitor, a PROTAC linker, and a cereblon-binding moiety, effectively disrupting FGFR2 signaling in gastric cancer cells. Its structural components facilitate targeted protein degradation, highlighting its potential in research focused on tumor biology. Reagent-grade; for laboratory research purposes only.
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