DusQ 2 succinimidyl ester is a derivative with an amine reactive group for labeling with the amine-modified oligonucleotides, amine-containing proteins and other molecules. DusQ 2 is a nonfluorescent quencher with an absorbance maximum of 552 nm. It is useful as an acceptor in fluorescence resonance energy transfer (FRET) applications, nucleic acid assays in conjunction with yellow and orange to red emitting dyes such as Cyanine3, Cyanine5, ROX, Texas Red, AF 555, AF 594, AF 647. NHS ester function allows to conjugate the quencher to various biomolecules of interest, and also to prepare oligonucleotides with DusQ 2.
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