1,2-Dioctanoyl PC is a synthetic analog of natural phosphatidylcholine species containing saturated C8:O fatty acids in the sn-1 and sn-2 positions of the glycerol backbone. 1,2-Dioctanoyl PC is a prodrug that is hydrolyzed by hydrochloric acid to form 1,2-dioctanoylglycerol. The fatty acid chain of t1,2-Dioctanoyl PC has been shown to be a PGP substrate and an inhibitor of PGP. As an inhibitor, 1,2-Dioctanoyl PC blocks the efflux of certain substrates from cells. Reagent grade, for research use only.
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