PLA(5k)-PEG(5k)-NH2 has terminal amine which can react readily with an active NHS ester or with a carboxylic acid in the presence of HATU/EDC. The polymer contains both hydrophobic (PLA) and hydrophilic (PEG) blocks. It can self-assemble in water to form nanoparticles/micelles which can be used to encapsulate biopharmaceutical drugs.
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