PLA(2k)-PEG(5k)-COOH has a racemic PLA hydrophobic block and a PEG hydrophilic block tethered with carboxyl which is reactive with amine in the presence of activating agent, such as HATU or EDC, to form a stable amide linkage. The polymer can self-assemble to form micelles in water and be used to encapsulate drugs in drug delivery.
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