Gambogic acid

Gambogic acid

Gambogic acid is a natural product isolated from the resin of Garcinia hurburyi tree, Gambogic acid is a potent apoptosis inducer. It binds covalently to the regulatory subunit B (SPTSSB) of the serine palmitoyltransferase complex and inhibits de novo sphingolipid biosynthesis.

Molecular structure of the compound BP-22199
    • Unit
    • Price
    • Qty
    • 100 MG
    • $125.00
    • 500 MG
    • $320.00
    • 1 G
    • $560.00
    • 5 G
    • $2200.00

Usually ships within 24 hours.

Would you like to inquire about custom quantity?
Inquire

Product Citations

  1. Babalola, K. T., Ganugula, R., Arora, M., Anderson, D., Agarwal, S. K., Mohan, C., ... & Kumar, M. R. (2025). Dose optimization of lymph node-targeted cyclosporine-A for lupus-driven vasculopathy. Journal of Controlled Release, 114553.
    https://www.sciencedirect.com/science/article/abs/pii/S0168365925011678
  2. Choudhury, N., Majeti, S., Lee, N., Thakur, G. A., Kumar, M. R., Arora, M., & Ganugula, R. (2025). Dual-Ligand Targeted Nanoparticles Enhance In Vitro Delivery and Efficacy of Investigational Drug Candidate GAT211. ACS Applied Bio Materials.
    https://pubs.acs.org/doi/abs/10.1021/acsabm.5c01430
  3. Kwan HY, Xu Q, et al Targeted Chinese Medicine Delivery by A New Family of Biodegradable Pseudo-Protein Nanoparticles for Treating Triple-Negative Breast Cancer: In Vitro and In Vivo study. Frontiers in Oncology. 2021. 10
    https://www.frontiersin.org/articles/10.3389/fonc.2020.600298/full
  4. Pula, W., Ganugula, R., Esposito, E., Kumar, M. R., & Arora, M. (2024). Engineered urolithin A-laden functional polymer-lipid hybrid nanoparticles prevent cisplatin-induced proximal tubular injury in vitro. European Journal of Pharmaceutics and Biopharmaceutics, 200, 114334.
    https://www.sciencedirect.com/science/article/abs/pii/S0939641124001607
  5. R. Ganugula, M. Arora, S. Dwivedi, D. S. Chandrashekar, S. Varambally, E. M. Scott, and M. N. V. Ravi Kumar.Systemic Anti-Inflammatory Therapy Aided by Curcumin-Laden Double-Headed Nanoparticles Combined with Injectable Long-Acting Insulin in a Rodent Model of Diabetes Eye Disease. ACS Nano. 2023 17 (7), 6857-6874. DOI: 10.1021/acsnano.3c00535
    https://pubs.acs.org/doi/full/10.1021/acsnano.3c00535
  6. Saini, P., Ganugula, R., Arora, M., & Kumar, M. R. www. nature. com/scientificreports OPEN The Next Generation Non-competitive Active Polyester Nanosystems for Transferrin Received: 31 May 2016.
    https://oaktrust.library.tamu.edu/server/api/core/bitstreams/062468a2-0b02-4350-a05d-7642ef5fb8b0/content
  7. Wahab, A. T., Nuthalapati, N. K., Harwood, J. T., Ganugula, R., Arora, M., & Kumar, M. R. (2025). Urolithin A-laden functional nanoparticles alleviate cisplatin-induced cardiotoxicity in mice by inhibiting inflammation-induced lymphangiogenesis. Free Radical Biology and Medicine, 237, 491-502.
    https://www.sciencedirect.com/science/article/abs/pii/S0891584925007646
  8. Xu Q, Chu CC Development of ROS-responsive amino acid-based poly(ester amide) nanoparticle for anticancer drug delivery. Journal of Biomedical Materials Research. 2020. 109(4). pp. 524-537
    https://onlinelibrary.wiley.com/doi/abs/10.1002/jbm.a.37035