Lipid 5
Lipid 5, also known as 7-[(2-Hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]heptyl 2-octyldecanoate, is a derivative of ALC-0315. It serves as a synthetic, ionizable lipid in conjunction with other lipids to form lipid nanoparticles (LNPs) for drug delivery. The pKa is 6.2. Reagent grade, for research use only.

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Catalog:
BP-26127
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Name:
Lipid 5
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Formula:
C44H87NO5
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MW:
710.2
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CAS:
2089251-33-0
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Purity:
95%
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Ships Within:
24 Hours
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Storage Condition:
-20°C
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Solubility:
Ethanol, DMSO, DMF
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Shipping:
Ambient Temperature
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Availability:
In Stock
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NMR:
View
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SDS:
View
Product Citations
- Omo-Lamai, S., Wang, Y., Patel, M. N., Essien, E. O., Shen, M., Majumder, A., ... & Brenner, J. S. (2024). Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects. bioRxiv, 2024-04.
https://doi.org/10.1101/2024.04.16.589801