TCO-PEG3-amine

TCO-PEG3-amine

TCO-PEG3-amine is a click chemistry building block containing a TCO moiety and a free amine. Amine is very reactive with active NHS ester or with carboxylic acid in the presence of of activators suh as EDC. TCO moiety is very reactive with tetrazine ( 3rd generation click chemistry). Please contact us for GMP-grade inquiries. The half-life of TCO is short as it will naturally isomerize into CCO (cis-cycloctene) and lose the reactivity. TCO compound is not recommended for long term storage.

Molecular structure of the compound BP-24099
    • Unit
    • Price
    • Qty
    • 25 MG
    • $195.00
    • 100 MG
    • $560.00
    • 250 MG
    • $1100.00

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Product Citations

  1. Bork, I., Dombrowsky, C. S., Bitsch, S., Happel, D., Geyer, F. K., Avrutina, O., & Kolmar, H. (2024). Tailor-Made Bioactive Papers by Site-Specific and Orthogonal Covalent Immobilization of Proteins. Biomacromolecules, 25(8), 5300-5309.
    https://doi.org/10.1021/acs.biomac.4c00724