DM1

DM1

Mertansine, also called DM1 is a thiol-containing maytansinoid for therapeutic purposes. It can be attached to a monoclonal antibody through reaction of the thiol group with a maleimide linker to create an antibody-drug conjugate (ADC). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-23648
    • Unit
    • Price
    • Qty
    • 25 MG
    • $130.00
    • 50 MG
    • $260.00
    • 100 MG
    • $410.00
    • 250 MG
    • $860.00

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Product Citations

  1. Verhaar, E. R. (2024). Targeting MHC-I related proteins for cancer diagnosis and therap (Doctoral dissertation, Leiden University).
    https://scholarlypublications.universiteitleiden.nl/handle/1887/3766089
  2. Verhaar, E. R., Knoflook, A., Pishesha, N., Liu, X., van Keizerswaard, W. J., Wucherpfennig, K. W., & Ploegh, H. L. (2024). MICA-specific nanobodies for diagnosis and immunotherapy of MICA+ tumors. Frontiers in Immunology, 15, 1368586.
    https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1368586/full