Azido-PEG2-NHS ester

Azido-PEG2-NHS ester

Azido-PEG2-NHS ester is a click chemistry crosslinker containing an azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-20524
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    • Price
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    • 100 MG
    • $100.00
    • 500 MG
    • $280.00
    • 1 G
    • $440.00
    • 5 G
    • $1600.00

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Product Citations

  1. Liu K, Lat PK, et al CLICK-17, a DNA enzyme that harnesses ultra-low concentrations of either Cu+ or Cu2+ to catalyze the azide-alkyne ‘click’ reaction in water. Nucleic Acids Research. 2020. 48(13). pp. 7256-7370
    https://academic.oup.com/nar/article/doi/10.1093/nar/gkaa502/5855639
  2. Maksimova, E., Marcano, D. E. S., & De Roo, J. (2025). Quantification of azides on the surface of nanoparticles: towards precise bioconjugation.
    https://chemrxiv.org/engage/chemrxiv/article-details/67b722916dde43c908b286d4
  3. Mengzhe W, Christopher DM, Hui W, et al. The efficiency of 18F labelling of prostate specific membrane antigen ligand via strain-promoted azide-alkyne reaction: reaction speed versus hydrophilicity. The Royal Society of Chemistry. 2018.
    https://pdfs.semanticscholar.org/22f6/b8df3e348b76c8c3fc4cfe6adc8c0e237e1f.pdf