Azidoacetic acid NHS ester

Azidoacetic acid NHS ester

Azidoacetic acid NHS ester is a compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22467
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    • 100 MG
    • $142.00
    • 250 MG
    • $231.00
    • 1 G
    • $394.00
    • 5 G
    • $909.00

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Product Citations

  1. https://pubs.acs.org/doi/abs/10.1021/acs.biomac.5c01648
    Click Chemistry
  2. https://pubs.acs.org/doi/full/10.1021/acssensors.5c02311
    PEG linker
  3. Michael Graige, Christopher Macdonald. Determination of single cell and spatial protein information by recoding amino acid polymers into dna polymers. (WO2025155747A1)
    https://patents.google.com/patent/WO2025155747A1/en?q=(BROADPHARM)&oq=BROADPHARM&sort=new&page=3
  4. Piranej, S., Jackson, K., Zhang, L., Kæstel-Hansen, J., Sommerhage, F., DeRoo, D., ... & Salaita, K. (2025). Fuel-Free Rolosense: Viral Sensing Using Diffusional Particle Tracking. ACS sensors, 10(11), 8542-8553.
    https://pubs.acs.org/doi/full/10.1021/acssensors.5c02311
  5. Piranej, S., Ogasawara, H., Zhang, L., Jackson, K., Bazrafshan, A., & Salaita, K. (2025). On-Demand Photoactivation of DNA-Based Motor Motion. ACS nano.
    https://pubs.acs.org/doi/full/10.1021/acsnano.4c13068
  6. Piranej, Selma, Luona Zhang, Alisina Bazrafshan, Mariana Marin, Gregory B. Melikyan, and Khalid Salaita. Rolosense: Mechanical detection of SARS-CoV-2 using a DNA-based motor.. bioRxiv. 2023
    https://www.biorxiv.org/content/10.1101/2023.02.27.530294v1.full.pdf
  7. Siva Sankara, C., Shanbhag, A. R., Rincón Díaz, D., Hodges, C. A., Li, C., Harrison, J. K., & Zhang, F. (2025). Engineering pH-Responsive Dendrimer–STAT3 Inhibitor Conjugates for Intracellular Delivery. Biomacromolecules.
    https://pubs.acs.org/doi/abs/10.1021/acs.biomac.5c01648
  8. Velusamy, A., Sharma, R., Rashid, S. A., Ogasawara, H., & Salaita, K. (2024). DNA mechanocapsules for programmable piconewton responsive drug delivery. Nature Communications, 15(1), 704.
    https://www.nature.com/articles/s41467-023-44061-w
  9. 飛翼 中田, 研史 白兼, 佑二 吉光. Compound and labeled biomaterial using same. (WO2024181456A1)
    https://patents.google.com/patent/WO2024181456A1/en?q=(BROADPHARM)&oq=BROADPHARM&sort=new&page=14