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Flotetuzumab - Anti-Human CD123/CD3 Bispecific Antibody
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Flotetuzumab - Anti-Human CD123/CD3 Bispecific Antibody
Flotetuzumab - Anti-Human CD123/CD3 Bispecific Antibody
Catalog #: bp-50657
Catalog #
Unit
Price
Qty
BP-50657
1 MG
$750.00
BP-50657
5 MG
$2800.00
BP-50657
10 MG
$4300.00
Usually ships within 24 hours.
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Overview
Flotetuzumab (MGD006; S80880) is an investigational CD123/CD3 bispecific dual-affinity retargeting antibody (DART) molecule. Flotetuzumab reactivates T cells by simultaneously binding to CD123 in target cells and CD3 in effector T cells, leading to T-cell-mediated cytotoxicity in target cells. Flotetuzumab shows inhibitory effect on a mouse model of patient-derived xenograft (PDX) in acute myeloid leukemia (AML).
Product Details
Species Reactivity
Human
Source
Mammalian cells
Host/Isotype
V-Lambda-VH_V-Kappa-VH'
Class
Bispecific Antibody
Type
Recombinant Humanized
Conjugate
Unconjugated
Molecular Weight
58.77 kDa
Storage Condition
Store at -80°C for 2 years. Aliquots should be stored at the same temperature after first use to avoid multiple freeze-thaws.
Application
ELISA, FACS, Functional assay
Images
Datasheets and Documents
Datasheet BP-50657.pdf
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