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Ivonescimab– Anti-PD-1/VEGF Bispecific Antibody
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Ivonescimab– Anti-PD-1/VEGF Bispecific Antibody
Ivonescimab– Anti-PD-1/VEGF Bispecific Antibody
Catalog #: bp-50632
Catalog #
Unit
Price
Qty
BP-50632
1 MG
$650.00
BP-50632
5 MG
$1800.00
BP-50632
10 MG
$3000.00
Usually ships within 24 hours.
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Overview
Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody. Ivonescimab competitively inhibiting PD-1/PD-L1 interaction, reversing the immunosuppression mediated by it, and blocks the binding of VEGF-A to VEGFR2, inhibiting tumour angiogenesis in the tumour microenvironment. Ivonescimab also has significantly anticancer activity against EGFR-mutated locally advanced or metastatic non-squamous non-small cell lung cancer (NSCL).
Product Details
Species Reactivity
Human
Source
Mammalian cells
Host/Isotype
Human IgG1 (L234A/L235A) kappa
Class
Bispecific Antibody
Type
Recombinant Humanized
Conjugate
Unconjugated
Molecular Weight
201.1 kDa
Storage Condition
Store at -80°C for 2 years. Aliquots should be stored at the same temperature after first use to avoid multiple freeze-thaws.
Application
ELISA, FACS, Functional assay
Images
Datasheets and Documents
Datasheet BP-50632.pdf
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