Biotin-11-dATP is a deoxyadenosine nucleoside triphosphate analog that can be enzymatically incorporated into DNA/cDNA. The biotinylated nucleic acid strands can be detected/isolated using its affinity toward streptavidin (or other avidin). The approach has broad applications in many nucleic acid analysis methods including PCR, nick translation, reverse transcription, and surface hybridization.
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