NH2-PEG4-hydrazone-DBCO is a degradable ADC linker containing four PEG units, which can be used to construct antibody-drug conjugates (ADCs). NH2-PEG4-hydrazone-DBCO is a click chemistry reagent that carries a DBCO group, enabling it to undergo a ring-strain-assisted acetylene-azide cycloaddition (SPAAC) reaction with molecules containing an azide group.
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