PROTAC GPX4 degrader-4

PROTAC GPX4 degrader-4


PROTAC GPX4 degrader-4 is a GPX4 PROTAC degrader (DC50: 5.32 nM). PROTAC GPX4 degrader-4 inhibits the activity of RT4, T24, and J82 cancer cells (IC50 values are 0.09, 2.97, and 7.58 µM, respectively). PROTAC GPX4 degrader-4 increases lipid ROS levels and induces ferroptosis in T24 and RT4 cells. PROTAC GPX4 degrader-4 has antitumor activity in T24 tumor-bearing BALB/c nude mouse model. PROTAC GPX4 degrader-4 can be used for bladder cancer research.

Molecular structure of the compound BP-46424
    • Unit
    • Price
    • Qty
    • 1 MG
    • $320.00
    • 5 MG
    • $900.00
    • 10 MG
    • $1440.00

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