dAurAB5

dAurAB5


dAurAB5 is a dual Aurora-A (DC50 = 8.8 nM) and Aurora-B (DC50 = 6.1 nM) PROTAC degrader. dAurAB5 induces degradation of Aurora-A and Aurora-B, reduces N-Myc levels, and decreases viability in IMR32 neuroblastoma cells. dAurAB5 downregulates the levels of AAK1, PTK2, GAK, and TTK. dAurAB5 can be used to study cancers such as neuroblastoma.

Molecular structure of the compound BP-46405
    • Unit
    • Price
    • Qty
    • 1 MG
    • $570.00
    • 5 MG
    • $1430.00

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